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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR1I2
All Species:
20
Human Site:
S274
Identified Species:
48.89
UniProt:
O75469
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75469
NP_003880.3
434
49762
S274
L
P
I
E
D
Q
I
S
L
L
K
G
A
A
F
Chimpanzee
Pan troglodytes
A2T7D9
348
39540
V205
A
V
E
I
C
H
I
V
L
N
T
T
F
C
L
Rhesus Macaque
Macaca mulatta
Q8SQ01
434
49974
S274
L
P
I
E
D
Q
I
S
L
L
K
G
A
T
F
Dog
Lupus familis
XP_535750
898
98286
S738
L
P
I
E
D
Q
I
S
L
L
K
G
A
T
F
Cat
Felis silvestris
Mouse
Mus musculus
O54915
431
49549
S271
L
P
I
E
D
Q
I
S
L
L
K
G
A
T
F
Rat
Rattus norvegicus
Q9R1A7
431
49642
S271
L
P
I
E
D
Q
I
S
L
L
K
G
A
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O42392
451
51281
A285
L
T
A
E
D
Q
I
A
L
L
K
S
S
A
I
Frog
Xenopus laevis
O13124
422
48170
A256
L
I
A
E
D
Q
I
A
L
L
K
S
S
V
I
Zebra Danio
Brachydanio rerio
Q1L673
422
47645
A258
L
T
A
E
D
Q
I
A
L
L
K
S
S
A
I
Tiger Blowfish
Takifugu rubipres
Q9W5Z3
447
49514
T251
L
T
I
A
D
Q
I
T
L
L
K
A
A
C
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.3
95.3
40
N.A.
76.7
76.2
N.A.
N.A.
39.9
41
42.6
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
54.6
97.6
43.9
N.A.
86.1
85.7
N.A.
N.A.
58.3
58.7
59.2
38
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
60
53.3
60
60
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
73.3
66.6
73.3
66.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
30
10
0
0
0
30
0
0
0
10
60
30
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
20
0
% C
% Asp:
0
0
0
0
90
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
80
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
50
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
60
10
0
0
100
0
0
0
0
0
0
0
30
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
90
0
0
0
0
% K
% Leu:
90
0
0
0
0
0
0
0
100
90
0
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
90
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
0
30
30
0
0
% S
% Thr:
0
30
0
0
0
0
0
10
0
0
10
10
0
40
0
% T
% Val:
0
10
0
0
0
0
0
10
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _